Telavancin Activity Against a Global Collection of Staphylococcus aureus Clinical Isolates (2013–2015)

Pfaller MA, Mendes RE*, Sader HS, Duncan LR, Castanheira M, Shortridge D and Flamm RK

Published Date: 2017-11-22
DOI10.21767/2472-1093.100038
Visit for more related articles at

Abstract

Telavancin had MIC50, MIC90, and MIC100 values of 0.03, 0.06, and 0.12 μg/mL, respectively, against methicillinsusceptible (MSSA), methicillin-resistant (MRSA), and MRSA multidrug-resistant (MDR) subsets of Staphylococcus aureus. Isolates with elevated vancomycin MIC values (2 μg/mL) resulted in a telavancin MIC50 (0.06 μg/mL) 2-fold higher than isolates with lower vancomycin MIC results (telavancin MIC50, 0.03 μg/mL). However, telavancin had MIC90 and MIC100 results of 0.06 and 0.12 μg/mL (100% susceptible), respectively, regardless of methicillin-resistance phenotype.

open access journals, open access scientific research publisher, open access publisher
Select your language of interest to view the total content in your interested language

Viewing options

Flyer image

Share This Article